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The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high mortality rate.

A trial showed that cannabidiol reduced the frequency of convulsive seizures among children and young adults with the Dravet syndrome over a 14-week period but was associated with adverse events including somnolence and elevation of liver-enzyme levels.

Reference:

Orrin Devinsky, O., et al. (2017). Trial of cannabidiol for drug-resistant seizures in the Dravet Syndrome. The New England Journal of Medicine, vol. 376, 2011–2020.